This study describes the psychosocial and physiological health care ne
eds of persons with HIV/AIDS in hospital, outpatient home care, and lo
ng-term care settings. A cross-sectional descriptive design with 386 p
atients selected from the four settings was used to test between-setti
ng differences on Healthcare Needs Scales. Univariate analyses of vari
ance of scale and subscale scores and Kruskal-Wallis analyses of varia
nce by ranks on item scores were computed. There was neither a relatio
nship between psychosocial and physiological health care needs nor a d
istinctive pattern of needs across settings by HIV classification. The
patients' needs varied between settings on health behaviors/social su
pport, health management, and elimination/physical/sensory functions b
ut were guile similar in psychosocial/financial support and neurologic
al/digestive functions. These results question assumptions about the r
elationships among stage of HIV infection, level and type of health ca
re need, and type of setting and suggest that health system resources
and nursing care focus on both the psychosocial and physiological need
s of persons with HIV/AIDS using individualized protocols.