NONINVASIVE IN-VIVO MEASUREMENT OF BLOOD SPECTRUM BY TIME-RESOLVED NEAR-INFRARED SPECTROSCOPY

Investigation of rapid near-infrared (NIR) spectroscopy in combination with fibre optics for biomedical sensing is presented. Modern diode-a rray technology enables sensitive measurement of changes in tissue abs orbance caused by blood pulsation. In order to describe the dynamics o f this system a multi-layer model based on pulse wave theory is used. The evaluation of the pulsatile part of tissue absorbance at different wavelengths allows the construction of both pulsatile and static tiss ue spectra. The absorption monitoring of an injected bolus of indocyan ine green is presented as an example of non-invasive measurement of an arterial blood spectrum.