UVB VERSUS UVB PLUS CALCIPOTRIOL (MC-903) THERAPY FOR PSORIASIS-VULGARIS

It is well known that UVB therapy of psoriasis vulgaris is potentiated by the association with topical and oral drugs, while till now there have been very few reports on the association between WE and calcipotr iol. In order to evaluate the efficacy and tolerance of this associati on, we studied 19 patients with psoriasis vulgaris of mild severity (P ASI: 5-10), Each patient was treated with UVB and invited to apply cal cipotriol 50 mu g/g ointment twice a day on one lesion usually on elbo ws or knees in order to compare it with the opposite side. The evaluat ion of each lesion was performed before and after 4 weeks of therapy, Our data show that the association between UVB and calcipotriol is sig nificantly more effective than UVB therapy alone: 17 out of 19 patient s (89%) showed a greater improvement with UVB plus calciporiol as comp ared to UVB alone.