PERIOSTEAL RESPONSE TO TRANSIENT ISCHEMIA - HISTOLOGICAL STUDIES ON THE RAT TIBIA

Authors
SVINDLAND AD NORDSLETTEN L REIKERAS O SKJEDAL S
Citation
Ad. Svindland et al., PERIOSTEAL RESPONSE TO TRANSIENT ISCHEMIA - HISTOLOGICAL STUDIES ON THE RAT TIBIA, Acta orthopaedica Scandinavica, 66(5), 1995, pp. 468-472
Citations number
21
Categorie Soggetti
Orthopedics
Journal title
Acta orthopaedica Scandinavica → ACNP
ISSN journal
00016470
Volume
66
Issue
5
Year of publication
1995
Pages
468 - 472
Database
ISI
SICI code
0001-6470(1995)66:5<468:PRTTI->2.0.ZU;2-4
Abstract
Complete arrest of blood flow was induced for 4.5 hours in the left hi ndlimb of Wistar rats by a tourniquet applied proximally to the thigh. Histologically the periost of the tibial bone after 3 days showed mar ked hypertrophy and hyperplasia of the periosteal cells with an osteog en differentiation. This response is similar to the initial formation of external callus during fracture healing. Transient ischemia may be an important factor in initiating fracture healing.