A rare form of epithelial ovarian carcinoma in an adolescent female is
reported. Serous psammocarcinoma is a type of ovarian cancer that is
characterized by extensive psammoma body formation and has not been re
ported in this age group. Histopathologically, this tumor exhibits str
omal invasion, vascular invasion, epithelial cells with low to moderat
e nuclear atypia, nests of solid epithelial cells less than 15 cells i
n diameter, and psammoma bodies that involve at least 75% of papillae
or nests of cells. The patient underwent optimal surgical debulking an
d nine courses of adjuvant chemotherapy with carboplatinum and cycloph
osphamide and is currently disease free. The prognosis for this type o
f ovarian cancer is unclear, but it appears to be better than other fo
rms of epithelial ovarian cancer. (C) 1995 Academic Press, Inc.