HYPERRESPONSIVENESS OF GRANULOCYTES TO ANAPHYLATOXINS, C5A AND C3A, IN CHURG-STRAUSS-SYNDROME

Authors
TANAKA T ABE M MITSUYAMA T FUKUOKA Y SAKURADA T HARA N
Citation
T. Tanaka et al., HYPERRESPONSIVENESS OF GRANULOCYTES TO ANAPHYLATOXINS, C5A AND C3A, IN CHURG-STRAUSS-SYNDROME, Internal medicine, 34(10), 1995, pp. 1005-1008
Citations number
NO
Categorie Soggetti
Medicine, General & Internal
Journal title
Internal medicine → ACNP
ISSN journal
09182918
Volume
34
Issue
10
Year of publication
1995
Pages
1005 - 1008
Database
ISI
SICI code
0918-2918(1995)34:10<1005:HOGTAC>2.0.ZU;2-6
Abstract
A 50-year-old man with Churg-Strauss syndrome showed granulocytes (GNL s) which generated more superoxide anion (O-2(-)) than GNLs from healt hy subjects following in vitro stimulation with C5a or C3a. Production of O-2(-) subsided as the clinical symptoms improved with steroid tre atment. A hyperresponsiveness of GNLs may be involved in this disorder .