Bk. Muller et F. Bonhoeffer, MOLECULAR INACTIVATION - SPATIALLY AND TEMPORALLY DEFINED MOLECULAR KNOCKOUTS, Current biology, 5(11), 1995, pp. 1255-1256
Most monoclonal antibodies do not functionally inactivate the antigen
they recognize. This limitation can be overcome by localized chromopho
re-assisted laser inactivation (CALI) of specific antibody-linked prot
eins.