Sa. Hofstadler et al., HIGH-PERFORMANCE FOURIER-TRANSFORM ION-CYCLOTRON RESONANCE MASS-SPECTROMETRIC DETECTION FOR CAPILLARY ELECTROPHORESIS, HRC. Journal of high resolution chromatography, 19(11), 1996, pp. 617-621
We describe the current state of the on-line combination of capillary
electrophoresis (CE) electrospray ionization (ESI) Fourier transform i
on cyclotron resonance (FTICR) mass spectrometry (MS), and discuss asp
ects of the FTICR technique relevant to its use as a detection scheme
for on-line separations. Aspects including sensitivity, mass resolutio
n, duty cycle, and tandem mass spectrometric capabilities are discusse
d in the context of online separations with examples from the authors'
laboratory.