CHLORIDE CHANNEL-2 GENE (CLC2) MAPS TO CHROMOSOME-16 OF THE MOUSE, EXTENDING A REGION OF CONSERVED SYNTENY WITH HUMAN-CHROMOSOME-3Q

Citation
A. Lengeling et al., CHLORIDE CHANNEL-2 GENE (CLC2) MAPS TO CHROMOSOME-16 OF THE MOUSE, EXTENDING A REGION OF CONSERVED SYNTENY WITH HUMAN-CHROMOSOME-3Q, Genetical Research, 66(2), 1995, pp. 175-178
Citations number
22
Categorie Soggetti
Genetics & Heredity
Journal title
ISSN journal
00166723
Volume
66
Issue
2
Year of publication
1995
Pages
175 - 178
Database
ISI
SICI code
0016-6723(1995)66:2<175:CCG(MT>2.0.ZU;2-X
Abstract
The Clc2 gene of the mouse codes for the ubiquitously expressed chlori de channel ClC-2, a member of a family of at least seven voltage gated chloride channels, some of which are implicated in hereditary disease s. Using a mouse interspecies back-cross panel, we have mapped Clc2 to Chr 16, proximal to the somatostatin gene Smst, extending a region of documented conserved synteny to human Chr 3q.