Mjnc. Keirse et al., CONTROVERSIES - PRELABOR RUPTURE OF THE MEMBRANES AT TERM - THE CASE FOR EXPECTANT MANAGEMENT, Journal of perinatal medicine, 24(6), 1996, pp. 563-572
Review of the controlled comparisons between induction of labor and ex
pectant care after prelabor rupture of the membranes (PROM) at term in
dicates that they are not unhelpful for deciding which of the two opti
ons is best. This is, first, because there is a large potential for bi
as in the studies reported thus far. Second, the trials are rather het
erogeneous and they are comparisons more between early and late induct
ion than between induction and expectant care. Third, it is difficult
to weigh an increased risk of operative delivery with the induction po
licy against an apparently clear, but almost certainly biased, reducti
on in the rare occurrence of neonatal infection. With expectant care a
bout 70% of women will give birth within 24 hours and 85% within 48 ho
urs. The majority of these women will derive little, if any, benefit f
rom induction and a routine policy of induction of labor after PROM ca
nnot be justified on the basis of the data that are available.