ETHANOL DECREASES BASAL CYTOSOLIC-FREE CALCIUM-CONCENTRATION IN CULTURED SKELETAL-MUSCLE CELLS

Authors
COFAN M FERNANDEZSOLA J NICOLAS JM POCH E URBANOMARQUEZ A
Citation
M. Cofan et al., ETHANOL DECREASES BASAL CYTOSOLIC-FREE CALCIUM-CONCENTRATION IN CULTURED SKELETAL-MUSCLE CELLS, Alcohol and alcoholism, 30(5), 1995, pp. 617-621
Citations number
15
Categorie Soggetti
Substance Abuse
Journal title
Alcohol and alcoholism → ACNP
ISSN journal
07350414
Volume
30
Issue
5
Year of publication
1995
Pages
617 - 621
Database
ISI
SICI code
0735-0414(1995)30:5<617:EDBCCI>2.0.ZU;2-Q
Abstract
We analysed the effect of ethanol on basal cytosolic-free calcium conc entration ([Ca2+](i)) in cultured rat myocytes. Ethanol caused a dose- dependent decrease of the resting [Ca2+](i). Removal of ethanol was fo llowed by a transitory increase of [Ca2+](i) above the basal level. In cells chronically exposed to ethanol, [Ca2+](i) normalized to the pre vious level.