The risk of hepatitis B virus (HBV) infection for health-care workers
(HCWs) is well documented. Fortunately, effective pre- and postexposur
e prophylaxis in the form of hepatitis B vaccine and hepatitis B immun
oglobulin are available for the prevention of occupational HBV infecti
on. Although the occupational risk of hepatitis C virus (HCV) infectio
n is less well defined, it appears to be lower than the risk of HBV in
fection. Nevertheless, the long-term consequence of HCV infection fan
be serious. Effective pre- and postexposure treatments against HCV inf
ection are needed.