LOW-GRADE GLIOMAS

Supratentorial low-grade gliomas comprise a group of primary central n ervous system neoplasms with characteristics of neuroglial cells (i.e. , astrocytes and oligodendrocytes) and relatively low anaplastic poten tial, although through time they tend to behave more aggressively. Imm ediate surgical intervention and subsequent radiation therapy are advo cated by some workers; at present, however, it remains unclear whether early intervention prolongs survival or changes the natural history o f the disease, especially in those patients who present with a seizure and a normal interictal examination.