Purpose: We determine whether autologous blood donation significantly
decreases the need for homologous transfusions after radical prostatec
tomy. Materials and Methods: The effects of estimated blood loss and a
utologous donation on the rate of homologous transfusions were analyze
d in 3 groups of 100 consecutive patients treated between 1983 and 199
2. Results: Overall, donors were less likely than nondonors to receive
homologous blood. As median estimated blood loss decreased from 1,200
to 800 cc from groups 1 to 3 (p < 0.05), the incidence of nondonors r
equiring homologous blood decreased from 62 to 11% and that of autolog
ous units transfused decreased from 96 to 19%. Conclusions: With decre
asing blood loss, safe but stringent criteria for transfusion and impr
oved safety of the blood supply, autologous donation is an inefficient
method to lower the slight risk of complications following homologous
transfusion during radical prostatectomy.