EVALUATION OF THE DIAGNOSTIC-VALUE OF A S IMPLE SCREENING-TEST FOR TUBULOINTERSTITIAL PROTEINURIA

A simple screening test for tubulointerstitial proteinuria based on de termination of total urinary protein with benzetonium chloride and alb umin by a bromcresolgreen method is used by Bulgarian nephrological cl inics for more than 5 years. With a purpose to evaluate the diagnostic value of this method we compare its results (in 43 low-proteinuric pa tients, 23 suffered from glomerulopathies and 20 suffered from tubuloi nterstitial diseases) with results adopted with quantitative immunoche mical methods for individual urinary proteins (albumin, alpha(1)-micro globulin). Based on these results we are able to conclude that the est imated approach for characterizing the type of the proteinuria is suit able for the routine nephrological practice screening. In the cases wh ere more precize analysis of the urinary protein is necessary we have to use higher specific methods.