HIGHLY EFFICIENT ENANTIOSELECTIVE PAUSON-KHAND REACTIONS

Authors
HAY AM KERR WJ KIRK GG MIDDLEMISS D
Citation
Am. Hay et al., HIGHLY EFFICIENT ENANTIOSELECTIVE PAUSON-KHAND REACTIONS, Organometallics, 14(11), 1995, pp. 4986-4988
Citations number
31
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear
Journal title
Organometallics → ACNP
ISSN journal
02767333
Volume
14
Issue
11
Year of publication
1995
Pages
4986 - 4988
Database
ISI
SICI code
0276-7333(1995)14:11<4986:HEEPR>2.0.ZU;2-8
Abstract
Diastereomeric (alkyne)pentacarbonyldicobalt complexes containing the chiral phosphine ligand (R)-(+)-Glyphos have been synthesized and sepa rated chromatographically. The isolated, optically pure diastereomeric complexes have been employed in intermolecular Pauson-Khand reactions , using anhydrous N-methylmorpholine N-oxide as the reaction promoter under mild conditions, to give high yields of cyclopentenone products in good to excellent enantiomeric excesses.