NMR CHARACTERIZATION OF GUANINE DNA SITE ALKYLATED BY KAPURIMYCIN A3,AN ANTITUMOR ANTIBIOTIC FROM STREPTOMYCES SP

Authors
CHAN KL SUGIYAMA H SAITO I KARA M
Citation
Kl. Chan et al., NMR CHARACTERIZATION OF GUANINE DNA SITE ALKYLATED BY KAPURIMYCIN A3,AN ANTITUMOR ANTIBIOTIC FROM STREPTOMYCES SP, Phytochemistry, 40(5), 1995, pp. 1373-1374
Citations number
4
Categorie Soggetti
Plant Sciences
Journal title
Phytochemistry → ACNP
ISSN journal
00319422
Volume
40
Issue
5
Year of publication
1995
Pages
1373 - 1374
Database
ISI
SICI code
0031-9422(1995)40:5<1373:NCOGDS>2.0.ZU;2-#
Abstract
The kapurimycin A3-guanine adduct was formed by alkylation of the anti tumour antibiotic with d(CGCG)(2). The site of alkylation of the guani ne was confirmed by comparative NMR studies with N-7-methyl-guanine in DMSO-d(6).