MOLECULAR-BASES FOR THE CONSTRUCTION OF ARTIFICIAL IMMUNOGENS AND VACCINES BASED ON SYNTHETIC POLYIONS

Authors
KHAITOV RM
Citation
Rm. Khaitov, MOLECULAR-BASES FOR THE CONSTRUCTION OF ARTIFICIAL IMMUNOGENS AND VACCINES BASED ON SYNTHETIC POLYIONS, Allergy proceedings, 16(5), 1995, pp. 255-260
Citations number
NO
Categorie Soggetti
Allergy
Journal title
Allergy proceedings → ACNP
ISSN journal
10469354
Volume
16
Issue
5
Year of publication
1995
Pages
255 - 260
Database
ISI
SICI code
1046-9354(1995)16:5<255:MFTCOA>2.0.ZU;2-F
Abstract
The molecular and cellular mechanisms of action of synthetic polyions on immunogenesis are reviewed. The results of studies of principal pro perties of polyionic immunostimulators and of the cell responses to th e action of these stimulants have been used to construct artificial an tigen-polyion complexes with enhanced immunogenic properties. The immu nizing properties of such macromolecular complexes, constructed with t he use of bacterial or viral antigens, are analyzed.