The pathophysiological mechanisms underlying trigeminal neuralgia are
not clearly understood and several therapeutic modalities have been ad
vocated. Microvascular decompression (MVD) is a widely used surgical a
pproach for the decompression of the affected root entry zone (REZ) of
the fifth cranial nerve. In this paper, we present our experience bas
ed on 32 patients with trigeminal neuralgia who were treated with MVD,
and discuss the role of this procedure in the surgical management of
trigeminal neuralgia. All patients had typical TN pain and had had pre
vious medical management which was unsuccessful. Fourteen patients (44
%) had been previously treated with other surgical procedures and had
persisting pain at the time of admission. Preoperatively, computerized
tomography was obtained in all patients; twelve patients (37.5%) were
evaluated with magnetic resonance imaging. These neuroradiological st
udies revealed an asymmetrical vascular structure at the involved REZ
in nine patients (28%). All patients underwent MVD, and a vascular loo
p causing compression on the REZ of the fifth cranial nerve was demons
trated in each case. No mortality was observed, and the only permanent
morbidity was cerebellar infarction in one patient (3%). Symptoms dis
appeared in all patients in the early postoperative period, and only t
hree recurrences (12%) were observed within the follow-up period (mean
: 26 months).