MULTICENTER EVALUATION OF CAPTURE ASSAY RADIM LIQUID ALLERGEN FOR MEASUREMENT OF SPECIFIC IGE ANTIBODIES

A multicentre trial of Capture Assay Radim Liquid Allergen was perform ed to define the sensitivity, specificity and clinical reliability of the system in diagnostic allergology. The results of the evaluation we re compared with clinical data and in vivo testing. Good agreement was obtained for Dermatophagoides pteronyssinus (D1), Cat's epithelium (E 1), Betula verrucosa (T3) and Olea europea (T9), Artemisia vulgaris (W 6) and Parietaria officinalis (W19). Some spreading of data was observ ed for Artemisia absinthium (W5), Cynodon dactylon (G2), and Lolium pe renne (G5). We found a high number of negative cases for Alternaria al ternata (M6). The advantages offered by the system are the automation, the small quantity of serum requested, the supply of quantitative res ults in international units of specific IgE, the user-friendly softwar e. The data are sufficiently reliable for the diagnostic system to be introduced into the clinical laboratory allergological routine.