The term ''trichrome vitiligo'' has been used to describe lesions of v
itiligo that have an intermediate level of color between the achromic
center and the peripheral unaffected skin. We describe a 12-year-oId b
lack girl with a generalized pigmentary disorder that fist appeared wh
en she was 3 years of age. Five shades of colors-white, tan, medium br
own (unaffected skin), dark brown, and black-were present. Biopsy spec
imens of the depigmented areas showed a complete absence of melanocyte
s, whereas the most hyperpigmented areas were characterized by an incr
ease in epidermal pigment and number of melanocytes. The lack of any p
receding inflammation in the affected areas and the subsequent widespr
ead spontaneous depigmentation that occurred within 1 year pointed to
a diagnosis of ''pentachrome vitiligo.''