EFFECTIVE TREATMENT WITH ALPHA(1)-PROTEASE INHIBITOR OF CHRONIC CUTANEOUS VASCULITIS ASSOCIATED WITH ALPHA(1)-ANTITRYPSIN DEFICIENCY

Authors
DOWD SK RODGERS GC CALLEN JP
Citation
Sk. Dowd et al., EFFECTIVE TREATMENT WITH ALPHA(1)-PROTEASE INHIBITOR OF CHRONIC CUTANEOUS VASCULITIS ASSOCIATED WITH ALPHA(1)-ANTITRYPSIN DEFICIENCY, Journal of the American Academy of Dermatology, 33(5), 1995, pp. 913-916
Citations number
39
Categorie Soggetti
Dermatology & Venereal Diseases
Journal title
Journal of the American Academy of Dermatology → ACNP
ISSN journal
01909622
Volume
33
Issue
5
Year of publication
1995
Part
2
Pages
913 - 916
Database
ISI
SICI code
0190-9622(1995)33:5<913:ETWAIO>2.0.ZU;2-8
Abstract
The primary serum proteinase inhibitor is alpha(1)-antitrypsin, and de ficiency of this enzyme has been associated with a variety of systemic and cutaneous disorders. We report cutaneous vasculitis in a 49-year- old man with alpha(1)-antitrypsin deficiency. His condition persisted despite treatment with colchicine, prednisone, and antibiotics but has been controlled by the administration of alpha(1)-protease inhibitor.