The case of an 81-year-old man with relapsing linear acantholytic derm
atosis is described. This is the second description of this disease en
tity, which is characterized by the histopathologic and ultrastructura
l features of Hailey-Hailey disease. Clinically, it is characterized b
y skin lesions that wax and wane in a systematic pattern following the
lines of Blaschko.