CENTRAL HYPOTHYROIDISM RESULTING FROM PITUITARY SUPPRESSION AND PERIPHERAL THYROTOXICOSIS IN A PREMATURE-INFANT BORN TO A MOTHER WITH GRAVES-DISEASE

Authors
HASHIMOTO H MARUYAMA H KOSHIDA R OKUDA N SATO T
Citation
H. Hashimoto et al., CENTRAL HYPOTHYROIDISM RESULTING FROM PITUITARY SUPPRESSION AND PERIPHERAL THYROTOXICOSIS IN A PREMATURE-INFANT BORN TO A MOTHER WITH GRAVES-DISEASE, The Journal of pediatrics, 127(5), 1995, pp. 809-811
Citations number
8
Categorie Soggetti
Pediatrics
Journal title
The Journal of pediatrics → ACNP
ISSN journal
00223476
Volume
127
Issue
5
Year of publication
1995
Pages
809 - 811
Database
ISI
SICI code
0022-3476(1995)127:5<809:CHRFPS>2.0.ZU;2-S
Abstract
We observed the sequential changes in serum thyroid hormones and thyro id-stimulating hormone receptor antibodies in an infant born at 30 wee ks of gestation to a mother with florid Graves disease. Transient cent ral hypothyroidism caused by pituitary suppression was observed after the resolution of peripheral thyrotoxicosis induced by thyroid-stimula ting antibody. Central hypothyroidism became overt when the suppressio n of the pituitary gland after fetal thyrotoxicosis was combined with weak activity of thyroid-stimulating antibody after birth.