Although reconstruction after mastectomy offers an opportunity for cos
metic rehabilitation that should make mastectomy more acceptable and c
ontribute to overall rehabilitation, the procedure is relatively under
utilized. The best cosmetic results usually come from breast conservat
ion rather than from mastectomy and subsequent reconstruction, and mos
t small (T0-T2) cancers can be treated by means of breast-conserving m
easures, The surgeon who is performing the mastectomy plays a key role
in explaining reconstruction to the patient and encouraging her to co
nsider the process. Surgeons and patient-related factors contribute to
under-utilization. Physician assessment of the results of reconstruct
ion, particularly with use of implants, tends to be less favorable tha
n that of the patient. Surgeons may overemphasize the inadequacies of
the results and patients may be overwhelmed by the diagnosis and array
of decisions that must be made. Immediate reconstruction poses Little
risk of treatment delay or limitation. Reconstruction after mastectom
y does not interfere with follow-up for recurrence, Choices for recons
truction have been limited by the withdrawal of silicone implants from
the market. The availability of reconstruction has encouraged the ina
ppropriate use of mastectomy for low risk disease. Prophylactic mastec
tomies and reconstruction should be performed for appropriate indicati
ons. To be effective, prophylactic mastectomy must include the nipple
areolar complex. The availability of genetic testing to define very hi
gh risk groups brings into question the adequacy of protection offered
by this procedure. Whereas prophylaxis in humans for premalignant mas
topathy appears to be nearly complete, mastectomy appears to offer lit
tle protection in a rodent carcinogen model. The effectiveness of mast
ectomy for prophylaxis in a genetically high risk human population is
unknown.