LONG-TERM CLINICAL AND ECHOCARDIOGRAPHIC FOLLOW-UP AFTER SURGICAL-CORRECTION OF HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY WITH EXTENDED MYECTOMY AND RECONSTRUCTION OF THE SUBVALVULAR MITRAL APPARATUS
Fa. Schoendube et al., LONG-TERM CLINICAL AND ECHOCARDIOGRAPHIC FOLLOW-UP AFTER SURGICAL-CORRECTION OF HYPERTROPHIC OBSTRUCTIVE CARDIOMYOPATHY WITH EXTENDED MYECTOMY AND RECONSTRUCTION OF THE SUBVALVULAR MITRAL APPARATUS, Circulation, 92(9), 1995, pp. 122-127
Background The standard surgical approach to hypertrophic obstructive
cardiomyopathy (HOCM) was modified in the present series with a combin
ation of extended myectomy with partial excision and mobilization of t
he papillary muscles. Methods and Results Between 1979 and 1992, 58 pa
tients (38 men and 20 women; mean age; 49+/-24 years) with HOCM were o
perated on with the use of this different technique. Their intraventri
cular gradients were 79+/-33 (+/-SD) mm Hg at rest and increased to 14
7+/-48 mm Hg with provocative maneuvers. Mild-to-moderate mitral regur
gitation was present in 60% of the patients, and severe regurgitation
was present in 5%. Ten patients required additional aortocoronary bypa
ss graft surgery. Follow-up (mean, 84 months) was complete (100%). Hem
odynamic improvement was documented by a significant (P<.01) decrease
in left ventricular end-diastolic pressure from 19+/-9 to 14+/-6 mm Hg
and reduction of basal outflow tract gradients to 5+/-7 nlm Hg at res
t and 16+/-24 mm Hg after provocation. Late mortality was 1.4% per pat
ient-year, and no sudden cardiac deaths occurred during follow-up, Fun
ctional status was excellent for 84% of the patients; 8 patients were
in New York Heart Association functional class III, and none were in c
lass IV. Echocardiography revealed no outflow tract obstruction.Conclu
sions Extended myectomy and reconstruction of the subvalvular mitral a
pparatus in HOCM result in excellent functional improvement with relie
f of outflow tract obstruction. The technique can be performed safely
despite its more aggressive surgical nature and allows an individualiz
ed strategy depending on the patient's extent and distribution of left
ventricular hypertrophy.