Y. Kosakai et al., MODIFIED MAZE PROCEDURE FOR PATIENTS WITH ATRIAL-FIBRILLATION UNDERGOING SIMULTANEOUS OPEN-HEART-SURGERY, Circulation, 92(9), 1995, pp. 359-364
Persistent atrial fibrillation (AF) leaves patients symptomatic and at
increased risk of thromboembolism even after otherwise successful car
diac surgery. Methods and Results To treat AF secondary to cardiac les
ions requiring surgery, we combined a modified maze procedure in 101 p
atients simultaneously undergoing valvular procedures (87), repair of
congenital anomalies (12), and other procedures (2), including 24 repe
at operations. Duration of AF varied from 0.1 to 30 years (average+/-S
D, 8.8+/-7.0 years); the f-wave voltage ranged from 0 to 0.45 mV (0.15
+/-0.09 mV); and cardiothoracic ratio varied from 40% to 99% (63+/-9%)
. Aortic cross-clamp time varied from 75 to 229 minutes (138+/-31 minu
tes), with bypass time ranging from 119 to 326 minutes (217+/-42 minut
es). There were two early deaths (2%), no late deaths, and one episode
of transient neurological ischemic attack in follow-up ranging from 1
.0 to 3.1 years, for a total of 190 patient-years. Postoperative rhyth
ms were sinus in 83 patients (82%), junctional in 4 (4%), and persiste
nt AF in 14 (14%), each of whom had mitral valve disease. Patients wit
h other underlying pathology had complete recovery of atrial rhythm. A
normal-sized A wave was detected in 88% for transtricuspid flow and i
n 73% for transmitral flow, suggesting concomitant recovery of atrial
contraction. Among 36 patients without mechanical valves, 30 (83%) wit
h atrial rhythm and contraction have been taken off anticoagulation th
erapy, including 10 who are free of all medication. Conclusions. The r
esults suggest that the combined approach is safe, effective, and indi
cated in patients who are judged capable of tolerating the procedure a
nd likely to regain atrial rhythm.