CALIBRATION STANDARD FOR LASER-DOPPLER PERFUSION MEASUREMENTS

The objective of the present study was the development of a new calibr ation standard for the laser-Doppler perfusion monitors. The beat freq uency spectrum obtained from a solution of latex spheres undergoing Br ownian motion was compared to that obtained from a porous polyethylene material containing the same solution. The mixture of static and dyna mic scattering events in the latter case was expected to produce a spe ctrum similar to that obtained in the real human tissue. The results o btained demonstrate clearly the difference between the signals recorde d from the commonly used motility standard which are the result of mul tiple Doppler shifting and homodyne mixing, and those generated from o ur enhanced model which predominantly result from single Doppler shift ing and heterodyne mixing. (C) 1995 American Institute of Physics.