SYNTHESIS AND SPECTROSCOPIC CHARACTERIZATIONS OF BOTH 10-METHOXY-3-METHYL-8-R(1)-6-R(2)-DIPYRAZOLO[3,4-B 4',3'-F][1,5]DIAZOCIN-5(1H)-ONES AND IPYRAZOLO[3,4-B/4',3'-F][1,5]DIAZOCINE-5,10-DIONES OF PHARMACEUTICAL INTEREST/

The non-selective methylation of compounds 3a-d using ethereal diazome thane, allowed the synthesis of isomers 4 and 5 which were useful inte rmediates for the preparation, by a simple approach, of the title comp ounds 7 and 9. A complete assignment of the chemical shifts to the car bon atoms of the compounds 7 and 9 was performed by different nmr expe riments, such as DEFT and XHDEPT for one-bond C-H correlations and COL OC experiments for long-range C-H correlations.