A CLINICOPATHOLOGICAL STUDY OF ADULT HISTIOCYTOSIS-X INVOLVING THE BRAIN

Authors
HASEGAWA K MITOMI T KOWA H MOTOORI T YAGISITA S
Citation
K. Hasegawa et al., A CLINICOPATHOLOGICAL STUDY OF ADULT HISTIOCYTOSIS-X INVOLVING THE BRAIN, Journal of Neurology, Neurosurgery and Psychiatry, 56(9), 1993, pp. 1008-1012
Citations number
21
Categorie Soggetti
Psychiatry,Neurosciences,"Clinical Neurology
Journal title
Journal of Neurology, Neurosurgery and Psychiatry → ACNP
ISSN journal
00223050
Volume
56
Issue
9
Year of publication
1993
Pages
1008 - 1012
Database
ISI
SICI code
0022-3050(1993)56:9<1008:ACSOAH>2.0.ZU;2-X
Abstract
Adult histiocytosis X involving the CNS caused progressive spastic par aparesis. The diagnosis was made by immunoreactive anti-S100 protein a ntibody staining and from the presence of Birbeck granules in biopsy s pecimens of skin lesions. Neuropathological examination showed massive proliferation and infiltration of S-100 containing histiocyte-like ce lls and reactive astrocytes throughout the CNS.