Nar. Munro et al., UPBEAT NYSTAGMUS IN A PATIENT WITH A SMALL MEDULLARY INFARCT, Journal of Neurology, Neurosurgery and Psychiatry, 56(10), 1993, pp. 1126-1128
A 43 year old man presented with decreased sensitivity in the left sid
e of the face and both upper limbs, and with upbeat nystagmus and skew
deviation. MRI demonstrated a well defined lesion compatible with an
infarct in the left side of the medulla, caudal and ventral to the ves
tibular nuclei, possibly involving the most caudal of the perihypoglos
sal nuclei, the nucleus intercalatus. Ocular motor studies, using an i
nfrared system, showed that the nystagmus slow phase decayed exponenti
ally, suggesting a failure of integration for vertical eye movements.
Vertical integration might, therefore, be performed partly in the nucl
eus intercalatus.