NUCLEOTIDE AND DEDUCED AMINO-ACID-SEQUENCES OF THE M-GENOME AND S-GENOME SEGMENTS OF 2 PUUMALA VIRUS ISOLATES FROM RUSSIA

Hemorrhagic fever with renal syndrome (HFRS) is caused by viruses in t he Hantavirus genus, family Bunyaviridae. Three serologically distinct hantaviruses, Hantaan, Seoul and Puumala viruses, are known to cause HFRS. We report here, for the first time, gene sequences of two human Puumala virus isolates, P360 and K27, obtained in an HFRS endemic regi on of the former Soviet Union. We compared the nucleotide sequences an d the derived amino acid sequences of their gene products to a Puumala virus isolate from rodents.