Rhodojaponin III is a grayanoid diterpene compound with insect anti-fe
edant and insecticidal properties. The compound was isolated from the
Chinese insecticidal plant Rhododendron molle (G. Don) and tested agai
nst five species of agricultural and stored-grain insects in laborator
y and greenhouse bioassays. At LC50 and EC50 (the effective concentrat
ion for 50% growth inhibition), rhodojaponin III was 198 to 218 times
more active for fall armyworm, Spodoptera frugiperda (J. E. Smith), la
rvae than for tobacco budworm, Heliothis virescens (F.), larvae. Resul
ts of tests with potted plants indicated that rhodojaponin III at 150
ppm reduced the plant damage index from 96 to 13% for S. frugiperda, f
rom 99 to 2% for Colorado potato beetle, Leptinotarsa decemlineata (Sa
y), and from 72 to 55% for greenbug, Schizaphis graminum (Rondani). Ag
ainst adults of the confused flour beetle, Tribolium confusum (Jacquel
in du Val), 50 ppm rhodojaponin III in flour caused 89% mortality and
totally inhibited fecundity. We obtained similar results with an ethyl
acetate extract of the dried flowers of R. molle.