The results of clinical and radiographic examinations of 15 dogs with
confirmed malignant histiocytosis (MH) were reviewed. The most common
clinical signs were anorexia (14 dogs), weight loss (13 dogs), letharg
y (13 dogs), anaemia (11 dogs), and dyspnoea and\or coughing (8 dogs).
Radiographs revealed abnormalities in all dogs, either intrathoracic
(pulmonary nodules or consolidation [7 dogs], mediastinal masses [10 d
ogs], and incidentally pleural effusion [3 dogs]) or abdominal (hepato
megaly [6 dogs] and splenomegaly [2 dogs]), or both. MH occurs relativ
ely frequently in Bernese Mountain dogs. Both clinical and radiographi
c signs are non-specific, but when they are present in a middle-aged B
ernese Mountain dog, MH should be included in the differential diagnos
is.