Rl. Greene et al., PERSONALITY-VARIABLES IN COCAINE-DEPENDENT AND MARIJUANA-DEPENDENT PATIENTS, Journal of personality assessment, 61(2), 1993, pp. 224-230
Khantzian (1985) hypothesized that the drug of choice of patients with
substance-dependence disorders reflects an attempt at self-medication
. Cocaine- and marijuana-dependent inpatients were compared using the
MMPI to test this hypothesis. Those two groups of patients did not dif
fer on the standard validity and clinical scales of the MMPI, and thei
r scores were basically similar to a group of alcohol-dependent inpati
ents and a group of psychiatric patients of similar age. There was no
single MMPI code type that was characteristic of either group of subst
ance-dependent patients. It appears that drug of choice had little eff
ect on the MMPI scores of these two groups of substance-dependent pati
ents. These results are not consistent with the theory of self-medicat
ion.