Background. A multidisciplinary wound care clinic was established to d
iagnose and treat patients with nonhealing ulcers of the lower extremi
ty. Methods. The clinic was organized under the direction of the depar
tments of vascular surgery and dermatology with support by the departm
ents of plastic surgery, hyperbaric medicine, orthopedic surgery, and
podiatry, and a research nurse. Results. In the first 4 years and 3 mo
nths, 683 patients were evaluated. One hundred seventy-one patients un
derwent outpatient testing in the noninvasive vascular laboratory and
30 patients underwent angiography. Causes of the ulcers were venous st
asis, 280 patients (41%); diabetic neuropathy, 182 patients (27%); art
erial insufficiency, 119 patients (17%); rheumatologic disorders, 38 p
atients (6%); trauma, 15 patients (2%); and in 49 patients (7%) a vari
ety of other disorders. One hundred seventy-nine operations were perfo
rmed including 86 operating room debridements, 48 amputations (43 toe,
4 below knee, 1 above knee), 23 arterial bypasses, 1 venous bypass, 1
4 skin grafts, 2 pedicle flaps, and 5 excisions of tumor. Fifty-six pa
tients with cellulitis were admitted to the hospital for intravenous a
ntibiotics and 12 patients were treated with hyperbaric oxygen therapy
. One-hundred thirty-two patients were entered into randomized prospec
tive trials of topical growth factors on Institutional Review Board ap
proved protocols. Conclusion. We concluded that a multidisciplinary ap
proach to wound care is beneficial to patients with chronic wounds and
provides a mechanism for clinical investigation on the healing of pro
blem wounds.