Background. Outcome for most abdominal wall defects is related to the
presence or absence of additional anomalies or prematurity. In gastros
chisis, outcome is almost as closely related to the severity of the in
flammatory ''peel'' on bowel that is thought to result from direct con
tact with amniotic fluid. Improving eviscerated bowel quality would be
expected to reduce morbidity in these patients. Methods. From 1986 to
1991, 32 patients with the antenatal diagnosis of gastroschisis were
treated. All were delivered by cesarean section; 13 surgical repairs w
ere made immediately in the delivery room. Surgical repairs in 19 pati
ents were made at less than 6 hours of age after transfer from the del
ivering hospital to the pediatric surgery center. Results. Thirty perc
ent of infants who underwent surgical repair in delivery room and 32%
of infants who underwent urgent surgical repair were either premature
or had significant associated anomalies, Seventy-three percent of deli
very room repair group had fascial repairs compared with 3 7% in the t
ransferred group. When infants more than 34-weeks' gestation without a
ssociated anomalies are compared with transferred infants, delivery ro
om repair group underwent more frequent fascial repair (8 of 9 vs 5 of
13, p < 0.03), were extubated sooner (2.9 vs 7.4 days, p < 0.04), tol
erated enteral feedings earlier (8.1 vs 22.2 days, p < 0.009), and req
uired fewer hospital days (13.6 vs 31.3 days, p < 0.01). Eviscerated b
owel of infants who underwent immediate surgical repair lacked the cha
racteristic matted, edematous, and fibrinous coated appearance seen in
transferred patients. Conclusions. Immediate delivery room repair of
gastroschisis results in increased fascial repairs and earlier extubat
ion, feeding, and hospital discharge. These benefits appear to be due
to the minimal reactive peel on eviscerated bowel at birth.