THE ILIZAROV FIXATOR AND POLYMETHYLMETHACRYLATE-ANTIBIOTIC BEADS FOR THE TREATMENT OF INFECTED DEFORMITIES

Eighteen of the 124 patients enrolled in the gentamicin methylmethacry late bead (GMB; Septopal) study had infected deformities that were tre ated with the Ilizarov external fixator. Nine of these patients (Group 1) were treated with an initial debridement and intravenous antibioti cs for four weeks. Nine patients (Group 2) were treated with GMB and, five days after operation, intravenous antibiotics. The two groups wer e similar. Group 1 included eight men and one woman (average age, 31.8 years) and Group 2, seven men and two woman (average age, 37.4 years) . Both groups had multiple deformities, including nonunions, segmental defects, angulation, and shortness. The end results were identical. E ight patients in each group had their infection successfully arrested (88.9%), and eight patients in each group had their deformity successf ully treated. The use of GMB with the Ilizarov fixator was as effectiv e as long-term parenteral antibiotics with the Ilizarov fixator for th e treatment of infected deformities.