Chronic anal fissures have a varied and often confusing clinical prese
ntation. To clarify this picture, we retrospectively studied 172 patie
nts to determine associations between patient characteristics and mani
festations of these lesions. We found that anterior fissures and senti
nel piles were significantly more common in women; pruritus and rectal
drainage occurred significantly more often in men; and patients with
a longer duration of symptoms and those with pruritus and drainage wer
e more likely to have a fistula. Younger patients were more likely to
report rectal bleeding. Patients with chronic anal pruritus or an anal
abscess should be carefully evaluated for an anal fistula, since anor
ectal problems may recur if a fistula remains untreated.