INHIBITION OF RECA-MEDIATED CLEAVAGE IN COVALENT DIMERS OF UMUD

Authors
LEE MH GUZZO A WALKER GC
Citation
Mh. Lee et al., INHIBITION OF RECA-MEDIATED CLEAVAGE IN COVALENT DIMERS OF UMUD, Journal of bacteriology, 178(24), 1996, pp. 7304-7307
Citations number
28
Categorie Soggetti
Microbiology
Journal title
Journal of bacteriology → ACNP
ISSN journal
00219193
Volume
178
Issue
24
Year of publication
1996
Pages
7304 - 7307
Database
ISI
SICI code
0021-9193(1996)178:24<7304:IORCIC>2.0.ZU;2-0
Abstract
Disulfide-cross-linked UmuD(2) derivatives were cleaved poorly upon in cubation with activated RecA. Reducing the disulfide bonds prior to in cubating the derivatives with RecA dramatically increased their extent of cleavage. These observations suggest that the UmuD monomer is a be tter substrate for the RecA-mediated cleavage reaction than the dimer.