Wt. Vigneswaran et al., DISEASE OF THE LEFT MAIN CORONARY-ARTERY - EARLY SURGICAL RESULTS ANDTHEIR ASSOCIATION WITH CAROTID-ARTERY STENOSIS, British Heart Journal, 70(4), 1993, pp. 342-345
Objectives-To review the results of surgical revascularisation for lef
t main coronary artery stenosis and the associated vascular pathology
that is responsible for cerebrovascular complication. Patients-60 pati
ents (45 men, 15 women) (mean age 61.3 (39-79)) who underwent revascul
arisation for stenosis of the left main stem coronary artery (LMS) bet
ween January 1987 and August 1990 were compared with an age and sex ma
tched control group of patients undergoing revascularisation for tripl
e vessel disease during the same period. Outcome measures-In-hospital
morbidity and operative mortality. Results-24 patients in the LMS grou
p presented with unstable angina. The left ventricular ejection fracti
on was less than 50% in 30 patients and less than 30% in nine. 17 pati
ents (28%) had large vessel extracranial carotid artery disease and 10
patients had vascular disease of the lower limbs. In six patients ath
eromatous plaques were noted in the ascending aorta during surgery. Th
ere was no in-hospital mortality. In-hospital morbidity included neuro
logical deficits in five (8.3%), arrhythmias in seven (11.6%), and pul
monary complications in six (10%) patients. The incidence of carotid a
rtery disease in the LMS group was significantly higher (p = 0.04). At
heromatous plaque in the ascending aorta and postoperative neurologica
l complications were more common patients with LMS. Conclusions-The in
cidence of carotid artery disease was higher and postoperative cerebro
vascular complications were more common in patients who had coronary a
rtery revascularisation for stenosis of the left main stem coronary ar
tery. The early surgical results were excellent. These findings sugges
t that for optimum perioperative management patients with stenosis of
the left main coronary artery should be screened for carotid artery di
sease before bypass surgery.