J. Hallas et al., DRUG-RELATED HOSPITAL ADMISSIONS - RESULTS FROM AN INTERVENTION PROGRAM, European Journal of Clinical Pharmacology, 45(3), 1993, pp. 199-203
As part of a high-intensity monitoring study of drug events as the cau
se of admission to departments of internal medicine, the effect of an
educational intervention programme was studied. Two departments were i
ncluded, one specialising in geriatrics and one that received patients
by non-selected referral. The series consisted of 607 consecutive adm
issions studied before and 703 after the intervention. The drug events
considered were adverse drug reactions and dose-related therapeutic f
ailures, mainly due to non-compliance. A modest, statistically non-sig
nificant decrease in drug related hospital admissions (DRH) was seen,
from 14 % before to 13 % after the intervention period. However, DRHs
classified as definitely avoidable showed the significant decrease of
83 %. There was no apparent relationship between the topics selected f
or the intervention programme and changes in the pattern of DRHs. No r
elationship between alterations in sales data and hospital admissions
caused by a given drug could be demonstrated. A blinded external evalu
ation of case abstracts did not disclose any significant shift in the
investigators' assessments. The intervention may have had an non-speci
fic effect on avoidable DRHs.