PROSTAGLANDIN PRODUCTION BY THE OOCYTE CUMULUS COMPLEX AROUND THE TIME OF FERTILIZATION AND THE EFFECT OF PROSTAGLANDIN-E ON THE DEVELOPMENT OF THE EARLY BOVINE EMBRYO

Authors
GUREVICH M HARELMARKOWITZ E MARCUS S SHORE LS SHEMESH M
Citation
M. Gurevich et al., PROSTAGLANDIN PRODUCTION BY THE OOCYTE CUMULUS COMPLEX AROUND THE TIME OF FERTILIZATION AND THE EFFECT OF PROSTAGLANDIN-E ON THE DEVELOPMENT OF THE EARLY BOVINE EMBRYO, Reproduction, fertility and development, 5(3), 1993, pp. 281-283
Citations number
8
Categorie Soggetti
Reproductive Biology","Developmental Biology
Journal title
Reproduction, fertility and development → ACNP
ISSN journal
10313613
Volume
5
Issue
3
Year of publication
1993
Pages
281 - 283
Database
ISI
SICI code
1031-3613(1993)5:3<281:PPBTOC>2.0.ZU;2-L
Abstract
The oocyte-cumulus complex (25 oocytes per 250 muL medium) produced pr ostaglandin-F2alpha (PGF2alpha) and PGE2 during maturation, immediatel y following fertilization and for at least 48 h after fertilization. T he data suggest that PG production is important in the development of the oocyte; addition of PGE2 (5 ng mL-1) to the fertilization medium i ncreased the rate of cleavage and groups of oocytes with low cleavage rates produced far less PG than groups with high cleavage rates. Measu rement of PG in the maturation medium could therefore be a means of as sessing the suitability of oocytes for fertilization.