Sp. Desai et Dl. Yuille, VISUALIZATION OF A RECURRENT CARCINOID-TUMOR AND AN OCCULT DISTANT METASTASIS BY TECHNETIUM-99M-SESTAMIBI, The Journal of nuclear medicine, 34(10), 1993, pp. 1748-1751
We present a case of atypical carcinoid that showed avid uptake of ses
tamib in a recurrent bronchial carcinoid tumor and a solitary, unsuspe
cted, occult, bony metastatic lesion in the distal femur. As carcinoid
tumors are known to be vascular, we suspect that its avidity for sest
amibi is secondary to increased blood flow, although other factors suc
h as the transmembrane potentials of plasma and mitochondrial membrane
s and relative number of mitochondria present in the cells of this car
cinoid tumor, may have also played a role.