SIMULTANEOUS EXTRACTION AND DETERMINATION OF SULFADIAZINE AND TRIMETHOPRIM IN MEDICATED FISH FEED BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

Authors
HORMAZABAL V STEFFENAK I YNDESTAD M
Citation
V. Hormazabal et al., SIMULTANEOUS EXTRACTION AND DETERMINATION OF SULFADIAZINE AND TRIMETHOPRIM IN MEDICATED FISH FEED BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY, Journal of chromatography, 648(1), 1993, pp. 183-186
Citations number
13
Categorie Soggetti
Chemistry Analytical
Journal title
Journal of chromatography → ACNP
Volume
648
Issue
1
Year of publication
1993
Pages
183 - 186
Database
ISI
SICI code
Abstract
A simple and rapid method for the simultaneous extraction and determin ation of sulfadiazine and trimethoprim in medicated fish feed by HPLC using sulfadimidine as internal standard is presented. The calibration curves were linear in the investigated areas, 1.25-10 mg/g of sulfadi azine and 0.25-2 mg/g trimethoprim. The recovery of sulfadiazine was 9 6-99%, and the recovery of trimethoprim 100-105%.