YEAST PROTEIN SERINE THREONINE PHOSPHATASES - MULTIPLE ROLES AND DIVERSE REGULATION/

Since the isolation of the first yeast protein phosphatase genes in 19 89, much progress has been made in understanding this important group of proteins. Yeast contain genes encoding all the major types of prote in phosphatase found in higher eukaryotes and the ability to use power ful genetic approaches will complement the wealth of biochemical infor mation available from other systems. This review will summarize recent progress in understanding the structure, function and regulation of t he PPP family of protein serine-threonine phosphatases, concentrating on the budding yeast Saccharomyces cerevisiae.