Jd. Tesorotess et al., HEART INVOLVEMENT IN LYMPHOMAS - THE VALUE OF MAGNETIC-RESONANCE-IMAGING AND 2-DIMENSIONAL ECHOCARDIOGRAPHY AT DISEASE PRESENTATION, Cancer, 72(8), 1993, pp. 2484-2490
Background and Methods. Thirty-six patients with mediastinal lymphoma
were studied with chest magnetic resonance imaging (MRI) and two-dimen
sional echocardiography at presentation to define the extent of the di
sease in the paracardiac area. Results. Involvement of cardiac structu
res was present in 23 of 36 patients (64%). Pericardial contiguity was
detected in 23 of 23 patients (100%) by MRI and in 18 of 23 patients
(78%) by echocardiography. Pericardial effusion, present in 17 patient
s (74%), and pericardial infiltration, present in 7 patients (30%), we
re detected by both techniques in 71% and 86%, respectively. Myocardia
l infiltration was identified in two of two patients (100%) by MRI and
in one of two patients (50%) by two-dimensional echocardiography. Ext
rapericardial disease was identified in 100% of patients by MRI but on
ly in 30% of patients by echocardiography. Conclusions. Extracardiac a
nd intracardiac involvement is a frequent event in mediastinal lymphom
as and should be carefully evaluated with different imaging modalities
, mainly MRI, for correct diagnosis and proper management.