IMOL 881, A NEW TRYPANOCIDAL COMPOUND

A new drug molecule (IMOL 881) was synthesized and is showing interest ing trypanocidal properties. test results on animal models indicate ac tivity against several trypanosome species, both in the veterinary and in the human medicine application fields. The species tested so far i nclude: T. evansi, T. equiperdum, T. gambiense and T. rhodesiense. The good activity combined with a relatively low toxicity results in a hi gh therapeutic index (> 100). In addition to its curative properties, the drug also seems to exhibit a prophylactic potential, as evidenced by tests on drug treated mice, subsequently infected with T. evansi.