N. Maeda et al., THE COMPLETE NUCLEOTIDE-SEQUENCE OF CHICKEN RIBOSOMAL PROTEIN-L7A GENE AND THE MULTIPLE FACTOR-BINDING SITES IN ITS 5'-FLANKING REGION, Biochimie, 75(9), 1993, pp. 785-790
The nucleotide sequence of the gene encoding chicken ribosomal protein
L7a was determined. The gene contains eight exons and seven introns,
which spread over 3613 nucleotides. The transcription initiation sites
were located on four consecutive nucleotides GCCC, which are at the 5
' terminus of a short polypyrimidine tract of eight base-pairs flanked
by G + C-rich regions. Neither a canonical TATA nor a CAAT box was fo
und in the 5'-flanking region. Instead, a short A + T-rich stretch was
found at the position where the TATA box is expected to be. There is
an intensive nuclear protein binding motif repeated four times in the
region -134 to -50. This motif is common to many ribosomal protein gen
es and may play an important role in the control of ribosomal protein
gene expression.