Recent advances in the enzymology and molecular biology of glycosyltra
nsferases - enzymes that catalyze the individual sugar attachment step
s in the process of protein and lipid glycosylation - have begun to yi
eld insights into how the expression of these enzymes is regulated. Th
ese results also provide us with an integrated view of the enzymatic a
nd molecular relationships of several glycosyltransferases and identif
y a number of novel glycosylation pathways.